Histochemical and biochemical studies on leukocyte alkaline phosphatase activity.

Long-Term Effect of Ciprofloxacin on Testicular Tissue: Evidence for Biochemical and Histochemical Changes

A histochemical procedure for localizing and evaluating leukocyte alkaline phosphatase activity in smears of blood and marrow.

By LEONARD S. KAPLOW T HE RESULTS of previous studies’8 on the histochemical localization of alkaline phosphatase activity in cells of blood and bomie marrow have been varied and contradictory. All such studies, except that of Vercauteren,8 were based on the Gomori-Takamutsu procedure.” ‘#{176}Numerous investigators”9 have shown that this procedure may produce false staimiing of nuclei and othe...

Leucocyte alkaline phosphatase and erythrocyte glucose-6-phosphate dehydrogenase in Down's Syndrome.

Following the discovery that Down's syndrome was due to trisomy, many investigators have reported increased activities of some cellular enzymes in mongoloid subjects (see review by Rosner, Ong, Paine, and Mahanand, 1965). The rationale underlying these studies is the possibility that the increased enzyme activities observed may reflect dosage effects of genes located on the trisomic chromosome....

Alkaline inorganic pyrophosphatase activity of mammalian-cell alkaline phosphatase.

Alkaline phosphatase prepared from mammalian cell cultures was found to have alkaline inorganic pyrophosphatase activity. Both of these activities appear to be associated with a single protein, as demonstrated by: (1) concomitant purification of alkaline phosphatase and alkaline inorganic pyrophosphatase; (2) proportional precipitation of alkaline phosphatase and inorganic pyrophosphatase activ...

An alarming biochemical side effect of Teucrium polium on the plasma membrane alkaline phosphatase of k562 cell line

The unexpected enhancement of alkalinee phosphatase (ALP) activity in the serum of a group of STZ-diabetic rats recieving the Teucrium polium extract (with hypoglycaemic property) may be attributed to its probable side effects. In order to get a more precise knowledge about this subject, we evaluated the effect of T. polium extract on the plasma membrane ALP activity of K562 cell line. Our data...